Integrated testing strategies (ITS) for safety assessment

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Integrated Testing Strategies (ITS) for safety assessment.

Integrated testing strategies (ITS), as opposed to single definitive tests or fixed batteries of tests, are expected to efficiently combine different information sources in a quantifiable fashion to satisfy an information need, in this case for regulatory safety assessments. With increasing awareness of the limitations of each individual tool and the development of highly targeted tests and pre...

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Integrated Testing Strategies ( ITS ) for Safety Assessment 1

CAAT Europe, University of Konstanz, Germany; L’Oréal R&I, Aulnay, France; Research Institute for Fragrance Materials, Inc., Woodcliff Lake, USA; DABMEB Consultancy Ltd, Sharnbrook, UK; INERIS, DRC/VIVA/METO, Verneuil en Halatte, France; Università degli Studi di Milano, Department of Health, Animal Science and Food Safety (VESPA), Milan, Italy; Università degli Studi di Milano, Department of P...

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Food for Thought ... Integrated Testing Strategies for Safety Assessments

Replacing a test on a living organism with a cellular, chemicoanalytical, or computational approach obviously is reductionistic. Sometimes this might work well, e.g., when an extreme pH is a clear indication of corrosivity. In general, however, it is naïve to expect a single system to substitute for all mechanisms, the entire applicability domain (substance classes), and degrees of severity. St...

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The deterioration of railway tracks raises great concerns about the integrity of assessments and evaluations of railway tracks currently in service. Integrated inspection strategies coupled with innovations in inspection technology can lead to significant improvements in operational cost efficiency and reliability without the requirement of a fundamental shift in the existing understanding o...

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Structural improvements at the vehicle front are state of the art in the field of pedestrian safety today and offer a basic passive protection. Meanwhile advanced safety systems have entered the market. Deployable systems, like the active bonnet or the windscreen airbag, further enhance the passive protection of passenger vehicles while systems of active safety such as autonomous emergency brak...

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ژورنال

عنوان ژورنال: ALTEX

سال: 2015

ISSN: 1868-596X

DOI: 10.14573/altex.1411011